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Serum Calcium Concentration in the Pathophysiology of Hypoparathyroidism

Hypoparathyroidism is deficiency of parathyroid hormone (PTH) which resulting in hypocalsemia and hyperphosphatemia. It involved calcium concentration which plays a vital role in the the pathophysiology and diagnosis of hypoparathyroidism. The following diagram shows the hydroxilation of vitamin D to its active form and its action to increase the serum calcium concentration. Find sections such the roles of PTH, vitamin D and calcitonin, detaile…

Category: Endocrinologist, Pathophysiology | Tags: , hypoparathyroidism, serum calcium concentration | 11:23 pm |

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Cushing’s Syndrome Pathophysiology Diagram and Guideline

negative feedback servo mechanism diagram of Cushing's Syndrome

Cushing’s Syndrome (hypercortisolism) is hormonal disorder caused by prolonged exposure of the body’s tissues to high levels of the hormone cortisol which can be from both serum ACTH low (iatrogenic, adrenal neoplasm) and serum ACTH high (pituitary neoplasm, ectopic ACTH). The pathophysiology diagram of Cushing’s Syndrome can be understood through the above illustration, since the outcome of this cycle is people develop Cushing’s syndrome becau…

Category: Endocrinologist | Tags: , Cortisol, Cushing’s Syndrome, Pathophysiology Diagram | 9:20 am |

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