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Bone Marrow Failure Syndroms in the Pathophysiology Concept of Aplastic Anemia

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Aplastic anemia is an immune-mediated disease where bone marrow does not produce sufficient new cells to replenish blood cells in the paradigm of the human bone marrow failure syndroms (wikipedia). Hematopoietic stem-cell compartment is the target for the immune response in the pathophysiology concept of Aplastic anemia. The following figure shows the immune destruction of hematopoiesis occured. Sections such Clinical associations, Pathophysiol…

The Basic Rules Algorithm Diagram of Acid/Base Disturbance

This algorithm diagram perform the basic acid-base balance and disturbance for such respiratory, metabolic and mixed problems related to the PaC02 and the pH. See the regulation of arterial pH includes, Simple acid/base disorders diagram (respiratory acidosis, metabolic alkalosis, respiratory alkalosis, metabolic acidosis), Diagnosis of acid-base disorders, and Renal acidosis instead of the algorithm diagram of acid/base disturbance. See com…